Alternative Names:
Apoptosis regulator Bcl-2; BCL2;
Application:
WB IHC ICC/IF FC
Reactivity:
Human Mouse
Dilution:
WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50
| Western blot analysis of Bcl-2 expression in (1) HeLa cell lysate; (2) NIH/3T3 cell lysate. |
| Immunohistochemical analysis of paraffin-embedded human tonsil, using Bcl-2 Antibody. |
| Immunofluorescent analysis of Jurkat cells, using Bcl-2 Antibody . |
| Taurine protects INS-1 cells from apoptosis induced by Di(2-ethylhexyl) phthalate via reducing oxidative stress and autophagy. -Toxicology Mechanisms and Methods |
| Mechanistic insights into geniposide regulation of bile salt export pump (BSEP) expression. -RSC Advances |
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Purification:
Affinity-chromatography
Specificity:
Bcl-2 Antibody detects endogenous levels of total Bcl-2
Immunogen:
A synthesized peptide derived from human Bcl-2
Description:
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
Storage Condition and Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.