Alternative Names:
glycogen synthase kinase 3 beta; GSK-3 beta; GSK3B; GSK3beta isoform;
Application:
WB IHC ICC/IF
Reactivity:
Human
Dilution:
WB 1:5000~1:10000 IHC 1:50~1:200 ICC/IF 1:50~1:200
| Western blot analysis of GSK3 beta (phospho S9) expression in 293T cell lysates, treated with Calyculin A. |
| Immunohistochemical analysis of paraffin-embedded human kidney, using Phospho-GSK3 beta (Ser9) Antibody. |
| Immunofluorescent analysis of HeLa cells treated with Calyculin A, using Phospho-GSK3 beta (Ser9) Antibody. |
| Benzene metabolite hydroquinone induces apoptosis of bone marrow mononuclear cells through inhibition of β-catenin signaling. -Toxicology in Vitro |
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Purification:
Affinity-chromatography
Specificity:
Phospho-GSK3 beta (Ser9) Antibody detects endogenous levels of total Phospho-GSK3 beta (Ser9)
Immunogen:
A synthesized peptide derived from human Phospho-GSK3 beta (Ser9)
Description:
GSK3B a proline-directed protein kinase of the GSK family. Phosphorylates and inactivates glycogen synthase. Participates in the Wnt signaling pathway. Involved in energy metabolism, neuronal cell development, and body pattern formation.
Storage Condition and Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.