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Alternative Names:

CYC; CYCS; Cytochrome c; HCS; THC4;

Application:

WB IHC ICC/IF IP

Reactivity:

Human Mouse Rat

Dilution:

WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:30

	Western blot analysis of Cytochrome C expression in Human kidney lysate.
	Immunohistochemical analysis of paraffin-embedded human liver, using Cytochrome C Antibody.
	Immunofluorescent analysis of Hela cells, using Cytochrome C Antibody.
	Taurine protects INS-1 cells from apoptosis induced by Di(2-ethylhexyl) phthalate via reducing oxidative stress and autophagy. -Toxicology Mechanisms and Methods
	Pyrroloquinoline quinine ameliorates doxorubicin-induced autophagy-dependent apoptosis via lysosomal-mitochondrial axis in vascular endothelial cells. -Toxicology
	Mechanistic insights into geniposide regulation of bile salt export pump (BSEP) expression. -RSC Advances

Purification:

Affinity-chromatography

Specificity:

Cytochrome C Antibody detects endogenous levels of Cytochrome C

Immunogen:

A synthesized peptide derived from human Cytochrome C

Description:

Cytochrome C is a well conserved electron-transport protein and is part of the respiratory chain localized to mitochondrial intermembrane space. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome C into the cytosol.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

CY5734.pdf