国产妓女性猛交亚洲AV性爱_日韩欧美国产精品亚洲二区_国产综合精品色在线_天堂av美女全裸在线观看_尤物视频国产在线观看_日本高清免费中文_欧美日韩粉嫩一区_色无码精品视频系列_a级毛片免费播放无码_久久亚洲AV成人一二三区

Alternative Names:

OSIL; Oxidative stress induced like; p60; p62; p62B; Paget disease of bone 3;PDB 3; PDB3;

Application:

WB ICC/IF FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:5000~1:10000 ICC/IF 1:50~1:200 FC 1:50

	Western blot analysis of p62/SQSTM1 expression in SKBR-3 cell lysate.
	Immunofluorescent analysis of Hela cells, using p62/SQSTM1 Antibody.
	Pyrroloquinoline quinine ameliorates doxorubicin-induced autophagy-dependent apoptosis via lysosomal-mitochondrial axis in vascular endothelial cells. -Toxicology
	Prostaglandin E1 Inhibited Diabetes-Induced Phenotypic Switching of Vascular Smooth Muscle Cells Through Activating Autophagy. -Cellular Physiology and Biochemistry
	MicroRNA-199a acts as a potential suppressor of cardiomyocyte autophagy through targeting Hspa5. -Oncotarget

Purification:

Affinity-chromatography

Specificity:

p62/SQSTM1 Antibody detects endogenous levels of total p62/SQSTM1

Immunogen:

A synthesized peptide derived from human p62/SQSTM1

Description:

Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

CY5546.pdf