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Alternative Names:

APG16 like 1; APG16L; APG16L beta; ATG16A; ATG16L; Atg16l1; IBD10; WD repeat domain 30; WDR30;

Application:

WB IHC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200

	Western blot analysis of Atg16L1 expression in HeLa cell lysate.

Purification:

Affinity-chromatography

Specificity:

Atg16L1 Antibody detects endogenous levels of total Atg16L1

Immunogen:

A synthesized peptide derived from human Atg16L1

Description:

Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

CY6909.pdf