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Alternative Names:

c-Myc; Class E basic helix-loop-helix protein 39; MRTL; MYC; Myc proto-oncogene protein; v-myc;

Application:

WB IHC ICC/IF IP FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50

	Western blot analysis of c-Myc expression in (1) Jurkat cell lysate;(2) K562 cell lysate.
	Immunohistochemical analysis of paraffin-embedded human lung cancer, using c-Myc Antibody.
	Immunofluorescent analysis of HeLa cells, using c-Myc Antibody.
	USP9X controls translation efficiency via deubiquitination of eukaryotic translation initiation factor 4A1. -Nucleic Acids Research
	miR‐139‐5p reverses stemness maintenance and metastasis of colon cancer stem‐like cells by targeting E2‐2. -JOURNAL OF CELLULAR PHYSIOLOGY

Purification:

Affinity-chromatography

Specificity:

c-Myc Antibody detects endogenous levels of total c-Myc

Immunogen:

A synthesized peptide derived from human c-Myc

Description:

Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Myc a proto-oncogenic transcription factor that plays a role in cell proliferation, apoptosis and in the development of human tumors.. Seems to activate the transcription of growth-related genes.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

CY5150.pdf