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Alternative Names:

E4TF1-60; E4TF1A; GABP subunit alpha; GABPA; human nuclear respiratory factor-2 subunit alpha; NFT2; NRF2; NRF2A;

Application:

WB IHC ICC/IF IP CHIP

Reactivity:

Human Mouse

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:100~1:500 IP 1:50

	Western blot analysis of Nrf2 expression in 293T cell treated with arsenite.
	Immunohistochemical analysis of paraffin-embedded human kidney, using Nrf2 Antibody.
	Immunofluorescent analysis of Hela cells, using Nrf2 Antibody.

Purification:

Affinity-chromatography

Specificity:

Nrf2 Antibody detects endogenous levels of total Nrf2

Immunogen:

A synthesized peptide derived from human Nrf2

Description:

Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

CY5136.pdf