Alternative Names:
GPX4; GSHPx-4; MCSP; mitochondrial; PHGPx; Phospholipid hydroperoxidase; snGPx; snPHGPx; Sperm nucleus glutathione peroxidase;
Application:
WB IHC ICC/IF
Reactivity:
Human Mouse Rat
Dilution:
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
| Western blot analysis of GPX4 expression in (1) HepG2 cell lysate; (2) Mouse testis lysate. |
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Purification:
Affinity-chromatography
Specificity:
GPX4 Antibody detects endogenous levels of total GPX4
Immunogen:
A synthesized peptide derived from human GPX4
Description:
Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage.
Storage Condition and Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.