Alternative Names:
CRK1; CSAID binding protein; CSBP; CSBP1; CSBP2; Cytokine suppressive anti- inflammatory drug binding protein; EC 2.7.11.24; MAP kinase MXI2; MAP kinase p38; MAPK14;
Application:
WB ICC/IF IP FC ChIP
Reactivity:
Human Mouse Rat
Dilution:
WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50 FC 1:30 ChIP 1:50
| Western blot analysis of p38 MAPK expression in (1) HeLa cell lysate; (2) NIH/3T3cell lysate; (3) PC-12 cell lysate. |
| Immunofluorescent analysis of Hela cells, using p38 MAPK Antibody . |
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Purification:
Affinity-chromatography
Specificity:
p38 MAPK Antibody detects endogenous levels of total p38 MAPK
Immunogen:
A synthesized peptide derived from human p38 MAPK
Description:
Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6.
Storage Condition and Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.