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Alternative Names:

Signal transducer and activator of transcription 5B; STA5B; STAT5; Stat5b; Transcription factor STAT5B;

Application:

WB IHC ICC/IF IP

Reactivity:

Human Mouse Rat

Dilution:

WB 1:1000~1:2000 IHC 1:1000~1:2000 ICC/IF 1:1000~1:2000 IP 1:40

	Western blot analysis of STAT5b expression in (1) HeLa cell lysate; (2) 3T3 cell lysate; (3) C6 cell lysate.
	Immunohistochemical analysis of paraffin-embedded human breast, using STAT5b Antibody.

Purification:

Affinity-chromatography

Specificity:

STAT5b Antibody detects endogenous levels of STAT5b

Immunogen:

A synthesized peptide derived from human STAT5b

Description:

Stat5 is activated in response to a wide variety of ligands including IL-2, GM-CSF, growth hormone and prolactin. Stat5 is constitutively active in some leukemic cell types. Phosphorylated Stat5 is found in some endothelial cells treated with IL-3, which suggests its involvement in angiogenesis and cell motility. Stat5a and Stat5b are independently regulated and activated in various cell types.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

CY5880.pdf